Anti-atherogenic Effect of Mulberry Leaf Tea in Atherogenic Index on Rats Dyslipidemia
نویسندگان
چکیده
Dyslipidemia is a lipid metabolism disorder characterized by fraction changes in the blood, such as an increase total cholesterol, LDL, TG and decrease HDL, which strongly associated with atherosclerosis. Mulberry leaves ( Morus alba L. ) contain quercetin 1-deoxynojirimycin (DNJ), help to lower cardiometabolic risk reducing hyperlipidemia, oxidative stress The objective of this study was determine effect mulberry leaf tea L.) on atherogenic index (AI) Sprague Dawley rats dyslipidemia. This true experimental research randomized pre post-test control group design. A 30 male (SD) were randomly divided into five groups. Calculation AI value: log (TG/HDL-C). Statistical analysis that used paired t-test one-way ANOVA test. intervention dosage 36 mg/100 g BW/day (P1) 72 (P2) significantly reduced values. Simvastatin P2 groups showed there no difference values after intervention. In conclusion, giving SD Abstrak: Dislipidemia merupakan kelainan metabolisme yang ditandai dengan perubahan fraksi dalam darah seperti peningkatan kolesterol total, dan penurunan HDL berhubungan kuat pada kejadian aterosklerosis. Daun mengandung kuersetin (DNJ) berguna menurunkan risiko kardiometabolik keadaan hiperlipidemia, oksidatif Tujuan dari penelitian ini untuk mengetahui pengaruh teh daun terhadap indeks aterogenik plasma (IAP) tikus dislipidemia. Penelitian post test Sebanyak ekor jantan dirandomisasi menjadi 5 kelompok. Rumus perhitungan nilai IAP : Analisis statistik digunakan adalah uji ANOVA. Intervensi dosis BB/hari secara signifikan plasma. Pada kelompok S menunjukkan bahwa tidak terdapat perbedaan setelah intervensi. Sehingga disimpulkan pemberian terbukti
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ژورنال
عنوان ژورنال: Jurnal Aisyah : jurnal ilmu kesehatan
سال: 2022
ISSN: ['2502-9495', '2502-4825']
DOI: https://doi.org/10.30604/jika.v7i3.1013